Sodium Stearyl Fumarate (TekLeu® SSF)

Sodium Stearyl Fumarate (SSF) is an inert, less hydrophobic alternative to magnesium stearate as a pharmaceutical tablet lubricant.

Molecule Structure

Features & Benefits

■ Improved drug stability.

■ Shorter disintegration times.

■ Faster dissolution rates.

■ Enhanced lubrication efficiency.

■ Harder tablets in comparison to tablets produced with magnesium stearat.

■ Faster formulation development and scale-up

Storage & Handling

Store in original, well-closed container protected from excessive heat and moisture.

Incompatible with chlorhexidine acetate.

Packing: 1kg Aluminum bag/ 5kg drum/ 20kg drum

Regulatory

DMF,CEP,GMP

Safety

Safety Data Sheet has been compiled for Sodium Stearyl Fumarate (SSF) that contains up-to-date information on questions relevant to safety.

■ As lubricants for tablets and capsules with a concentration of 0.5% ~ 3.0% (w/w). Typicals API as below:

■ It can form a protective coat film in effervescent tablets.

■ As this product has one fatty chain less and one hydrophilic group more compared with magnesium stearate, so it can solve the slow dissolution issue of magnesium stearate as lubricant.

■ Suitable for lubricants of razole drugs, which are easy to react with magnesium stearate and cannot use magnesium stearate as lubricant.

■ As a regulator and stabilizer, such as baked foods, floured thickened foods, baked potatoes and processed grains, with dosage for 0.2 %~ 1.0% of the food weight.