TekLeu® EO is a Low viscosity solvent for lipophilic actives.
Molecule Structure
CAS# | 111-62-6 |
EINECS# | 203-889-5 |
Features & Benefits
■ Non-occlusive emollient with good spreading properties.
■ Rapidly absorbed by body tissues. Dermal penetration enhancer.
Incompatibility
It can dissolve some rubbers and swell them.
It can also react with oxidants.
Storage & Handling
Stored in a small, full-filled, light-tight sealed container and in a cool, dry place.
If it is not full, it should be filled with nitrogen or other inert gas to replace the air to prevent the ethyl oleate from being oxidized. For long-term storage, antioxidants should be added.
Packing:1kg/bottle, 5kg/drum, 20kg/drum, 180kg/drum
Regulatory
DMF,CEP,GMP
Safety
Safety Data Sheet has been compiled for Ethyl Oleate (TekLeu® EO) that contains up-to-date information on questions relevant to safety.
Application
■ Used as a solvent, a transdermal absorption enhancer, a lubricant and a plasticizer in formulations.
■ A suitable solvent for steroids and other lipophilic drugs. Widely used in veterinary injections such as Cefquinoxime sulfate, enrofloxacin. Its properties are similar to almond oil and peanut oil, and its viscosity is low, and it is easily absorbed by body tissues.
■ Used as biodegradable microcapsules and microemulsions of cyclosporine implanted under the dermis.
■ As the solvent of flavor oil, the carrier of essence fragrance in field of food additives.
Physical & Chemical properties
Standard | CP2020; EP10.0; USP43-NF38; BP2020; GB 29938-2013 |
Appearance | Colorless to pale yellow clear liquid. |
Solubility | Almost insoluble in water, miscible with ethanol, dichloride methane or petroleum ether. It can be miscible with isopropanol in any proportion. |