Details Application Typical properties Resources

Ethyl Oleate (TekLeu® EO)

Frequently viewed resources

Details

TekLeu® EO is a Low viscosity solvent for lipophilic actives.

Molecule Structure

   

CAS#

111-62-6

EINECS#

203-889-5

 

 

Features & Benefits

■ Non-occlusive emollient with good spreading properties.

 

■ Rapidly absorbed by body tissues. Dermal penetration enhancer.

 

Incompatibility

It can dissolve some rubbers and swell them.

It can also react with oxidants.

 

Storage & Handling

Stored in a small, full-filled, light-tight sealed container and in a cool, dry place.

 

If it is not full, it should be filled with nitrogen or other inert gas to replace the air to prevent the ethyl oleate from being oxidized. For long-term storage, antioxidants should be added.

 

Packing:1kg/bottle, 5kg/drum, 20kg/drum, 180kg/drum

 

Regulatory

DMF,CEP,GMP

 

Safety

Safety Data Sheet has been compiled for Ethyl Oleate (TekLeu® EO)  that contains up-to-date information on questions relevant to safety.


Application

Application


■ Used as a solvent, a transdermal absorption enhancer, a lubricant and a plasticizer in formulations.

 

■ A suitable solvent for steroids and other lipophilic drugs. Widely used in veterinary injections such as Cefquinoxime sulfate, enrofloxacin. Its properties are similar to almond oil and peanut oil, and its viscosity is low, and it is easily absorbed by body tissues.

 

■ Used as biodegradable microcapsules and microemulsions of cyclosporine implanted under the dermis.

 

■ As the solvent of flavor oil, the carrier of essence fragrance in field of food additives.

 


Typical properties

Physical & Chemical properties

Standard

CP2020; EP10.0; USP43-NF38; BP2020; GB 29938-2013

Appearance

Colorless to pale yellow clear liquid.

Solubility

Almost insoluble in water, miscible with ethanol, dichloride methane or petroleum ether. It can be miscible with isopropanol in any proportion.